Process Integration & Synthesis using Chemical Engineering Standards
The AI-native platform
for process data
integration.
PISCES harmonizes data from disparate sources into a powerful interface for collaborative process design.
Extract insights, explore trade-offs, and understand your data better with Florence, our highly intelligent engineering co-pilot.
A growing public database
Our collection of public flowsheets is actively curated for quality and continuously expanding in coverage.
Explore diverse process designs
Browse, filter, and query flowsheets spanning fuels, chemicals, pharmaceuticals and food products. Every flowsheet is a structured, machine-readable graph you can view, analyze, and download, or copy into your personal library to iterate on.
Your data, your team, your models
Keep proprietary process data in secure, private shared workspaces visible only to your team. Comment, collaborate, and track every revision, then train custom models on your data to get the most intelligence out of it.
Private and secure
Share a workspace with only the members of your team. Your data never goes public.
Comment and collaborate
Discuss any unit or stream inline. Contributions are intuitive and stay in context.
Version history
Every flowsheet is versioned over time, so you can track changes and revisit any revision.
Custom-trained models
Build models on your private library to get the most intelligence from your own data.
North Star Biofuels
Private workspace
Comments on Fermenter R-201
Version history
- v3Updated fermenter conditionsjust now
- v2Added TEA assumptions2 days ago
- v1Imported from SuperProlast week
Analysis grounded in the flowsheet
Techno-economic and life-cycle assessment computed directly from the process graph, so every cost, return, and impact metric traces back to a specific unit and stream. No disconnected spreadsheets.
Annual economics
Millions USD, corn stover to ethanol
Feedstock dominates operating cost, the key lever for cellulosic ethanol economics.
Meet Florence
Florence brings chemical-engineering reasoning to every corner of PISCES. She cites her sources, proposes design revisions, and works across the platform, with an ever-expanding set of tools and capabilities.
TEA and LCA analysis
Work through techno-economic and life-cycle questions with numbers traced to the flowsheet.
Simulation copilot
Configure, run, and interpret rigorous process simulations from a harmonized flowsheet.
Flowsheet Builder
Describe a process in plain language and watch Florence assemble it on the canvas.
The whole process-engineering lifecycle
PISCES is more than a standard format. It is an end-to-end platform for managing process data, from extraction, validation and harmonization to analysis, simulation, and generative design. Built for collaboration and powered by AI.
Bring your data from anywhere
Decades of process data is scattered across PDFs, spreadsheets, and proprietary simulator files. PISCES brings it together in a unified platform designed for both human and AI readability.
Built on the Standard Flowsheet Format
SFF is an open, non-proprietary JSON standard that represents process flowsheets as directed graphs: unit operations are nodes, process streams are edges, and rich data attaches to both.
It is the FAIR knowledge-base backbone of PISCES. Everything we extract, simulate, and design speaks the same machine-readable language, so it stays findable, interoperable, and reusable.
{
"metadata": {
"sff_version": "1.0",
"source_document": "doi:10.1021/...",
"extraction_date": "2024-07-29"
},
"units": [
{
"id": "unit_1",
"type": "ChromatographyColumn",
"label": "Protein A Column"
},
{
"id": "unit_2",
"type": "Tank",
"label": "Elution Buffer Tank"
}
],
"streams": [
{
"id": "stream_1",
"source": "unit_2",
"destination": "unit_1",
"label": "Elution Buffer"
}
],
"chemicals": [
{
"id": "chem_1",
"name": "Tris-HCl",
"role": "buffer"
}
]
}One platform, end to end
Everything you need to manage, question, and analyze process data, unified around one open standard.
AI-powered extraction
Multimodal models read papers, figures, and spreadsheets and convert them into structured SFF, with a human reviewer in the loop.
FAIR knowledge base
A Findable, Accessible, Interoperable, and Reusable database of process flowsheets, openly available to the research community.
Private Workspaces
Organize flowsheets into a personal library and secure, shared workspaces, with collaboration and review built in.
Techno-economic and life-cycle assessmentComing soon
Quantify cost and environmental impact with transparent metrics traced to specific units and streams.
Process simulationComing soon
Run rigorous simulations directly from a harmonized flowsheet, without re-modeling in a separate tool.
Generative designComing soon
With a standardized database, Florence proposes candidate processes and optimizes existing ones from a plain-language brief.
The generative process design engine
Describe a process in plain language and Florence will assemble a candidate flowsheet, unit by unit and stream by stream. Trained on a standardized database, the design engine turns intent into a structured, simulate-ready starting point.
In development. Available to a limited set of users today.
Get the most intelligence out of your process data
Harmonize your data into one standard, then put AI to work on it: surface insights for scale-up and ground every techno-economic and life-cycle decision in the real flowsheet.