Process Integration & Synthesis using Chemical Engineering Standards
The AI-native platform
for process data
integration.
PISCES unifies process data into a collaborative interface for analysis, modeling, and design.
With Florence by your side, powerful AI insights are only a prompt away, and always grounded in domain expertise.
An expanding public database
Our public flowsheet database is constantly growing in size,
and actively curated for quality.
Explore diverse process designs
Browse, filter, and query flowsheets covering fuels, chemicals, pharmaceuticals,
food products, and more.
Your data, your team, your models
Keep proprietary data in secure, private workspaces visible only to you and your team. Comment, collaborate, and track every revision, then train custom models to get the most intelligence from your data.
Private and secure
Share a workspace with only the members of your team. Your data never goes public.
Comment and collaborate
Discuss any unit or stream inline. Contributions are intuitive and stay in context.
Version history
Every flowsheet is versioned over time, so you can track changes and revisit any revision.
Custom-trained models
Build models on your private library to get the most intelligence from your data.
North Star Biofuels
Private workspace
Comments on Fermenter R-201
Version history
- v3Updated fermenter conditionsjust now
- v2Added TEA assumptions2 days ago
- v1Imported from SuperProlast week
Analyze with confidence
Build rigorous techno-economic analyses and life-cycle assessments directly from process flowsheets. Adjust parameters, explore trade-offs, and compare different
design scenarios.
Annual economics
Millions USD, corn stover to ethanol
Feedstock dominates operating cost, the key lever for cellulosic ethanol economics.
Meet Florence
Florence brings process engineering expertise to every corner of PISCES.
Answering your data questions, proposing process improvements, and helping reason and iterate faster on flowsheet designs and analyses.
TEA and LCA analysis
Work through techno-economic and life-cycle questions with numbers traced to the flowsheet.
Simulation copilot
Configure, run, and interpret rigorous process simulations from a harmonized flowsheet.
Flowsheet Builder
Describe a process in plain language and watch Florence assemble it on the canvas.
The whole process-engineering lifecycle
PISCES is more than a standard format. It is an end-to-end platform for managing process data, from extraction, validation and harmonization to analysis, simulation, and generative design. Built for collaboration and powered by AI.
Bring your data from anywhere
Decades of process data is scattered across PDFs, spreadsheets, and proprietary simulator files. PISCES brings it together in a unified platform designed for both human and AI readability.
Built on the Standard Flowsheet Format
SFF is an open, non-proprietary JSON standard that represents process flowsheets as directed graphs: unit operations are nodes, process streams are edges, and rich data attaches to both.
It is the FAIR knowledge-base backbone of PISCES. Everything we extract, simulate, and design speaks the same machine-readable language, so it stays findable, interoperable, and reusable.
{
"metadata": {
"sff_version": "1.0",
"source_document": "doi:10.1021/...",
"extraction_date": "2024-07-29"
},
"units": [
{
"id": "unit_1",
"type": "ChromatographyColumn",
"label": "Protein A Column"
},
{
"id": "unit_2",
"type": "Tank",
"label": "Elution Buffer Tank"
}
],
"streams": [
{
"id": "stream_1",
"source": "unit_2",
"destination": "unit_1",
"label": "Elution Buffer"
}
],
"chemicals": [
{
"id": "chem_1",
"name": "Tris-HCl",
"role": "buffer"
}
]
}An end-to-end solution
Everything you need to import, manage, and analyze your process data in a secure and collaborative platform.
AI-powered extraction
Multimodal models read papers, figures, and spreadsheets and convert them into structured SFF, with a human reviewer in the loop.
FAIR knowledge base
A Findable, Accessible, Interoperable, and Reusable database of process flowsheets, openly available to the research community.
Private Workspaces
Organize flowsheets into a personal library and secure, shared workspaces, with collaboration and review built in.
Techno-economic and life-cycle assessmentComing soon
Quantify cost and environmental impact with transparent metrics traced to specific units and streams.
Process simulationComing soon
Run rigorous simulations directly from a harmonized flowsheet, without re-modeling in a separate tool.
Generative designComing soon
With a standardized database, Florence proposes candidate processes and optimizes existing ones from a plain-language brief.
Generative process design with Florence
Describe a process in natural language and Florence will help you build it unit by unit, stream by stream. Trained on our public flowsheet database, and equipped with domain expertise, Florence will help you go from idea to plausible design in minutes instead of months.
In development. Available to a limited set of users today.
One platform, infinite possibilities
PISCES re-defines the meaning of collaborative process design.